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A Long Childhood Feeds the Hungry Human Brain

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Findings in a recent study, reported by Erin White in a Northwestern University press release, give us insight into why human children take so long to grow and develop. The findings are an interesting read about brain development!

EVANSTON, Ill, August 25, 2014. — A five-year old’s brain is an energy monster. A new study led by Northwestern University anthropologists has found that it uses twice as much glucose (the energy that fuels the brain) as that of a full-grown adult.

The study helps to solve the long-standing mystery of why human children grow so slowly compared with our closest animal relatives.

The study shows that energy funneled to the brain dominates the human body’s metabolism early in life and is likely the reason why humans grow at a pace more typical of a reptile than a mammal during childhood. Results of the study were published the week of Aug. 25 in the journal Proceedings of the National Academy of Sciences.

“Our findings suggest that our bodies can’t afford to grow faster during the toddler and childhood years because a huge quantity of resources is required to fuel the developing human brain,” said Christopher Kuzawa, first author of the study and a professor of anthropology at Northwestern’s Weinberg College of Arts and Sciences. “As humans we have so much to learn, and that learning requires a complex and energy-hungry brain.”Kuzawa also is a faculty fellow at the Institute for Policy Research at Northwestern.

The study is the first to pool existing PET and MRI brain scan data — which measure glucose uptake and brain volume, respectively to show that the ages when the brain gobbles the most resources are also the ages when body growth is slowest. At 4 years of age, when this “brain drain” is at its peak and body growth slows to its minimum, the brain burns through resources at a rate equivalent to 66 percent of what the entire body uses at rest.

The findings support a long-standing hypothesis in anthropology that children grow so slowly, and are dependent for so long, because the human body needs to shunt a huge fraction of its resources to the brain during childhood, leaving little to be devoted to body growth. It also helps explain some common observations that many parents may have.

After a certain age it becomes difficult to guess a toddler or young child’s age by their size,” Kuzawa said. “Instead you have to listen to their speech and watch their behavior. Our study suggests that this is no accident. Body growth grinds nearly to a halt at the ages when brain development is happening at a lightning pace, because the brain is sapping up the available resources.”

It was previously believed that the brain’s resource burden on the body was largest at birth, when the size of the brain relative to the body is greatest. The researchers found instead that the brain maxes out its glucose use at age 5. At age 4 the brain consumes glucose at a rate comparable to 66 percent of the body’s resting metabolic rate (or more than 40 percent of the body’s total energy expenditure).

“The mid-childhood peak in brain costs has to do with the fact that synapses, connections in the brain, max out at this age, when we learn so many of the things we need to know to be successful humans,” Kuzawa said.

“At its peak in childhood, the brain burns through two-thirds of the calories the entire body uses at rest, much more than other primate species,” said William Leonard, co-author of the study. “To compensate for these heavy energy demands of our big brains, children grow more slowly and are less physically active during this age range. Our findings strongly suggest that humans evolved to grow slowly during this time in order to free up fuel for our expensive, busy childhood brains.” Leonard is professor and chair of the department of anthropology at Northwestern’s Weinberg College of Arts and Sciences.

This study was a collaboration between researchers at Northwestern University, Wayne State University, Children’s Hospital of Michigan, Icahn School of Medicine at Mount Sinai, University of Illinois, George Washington University and Harvard Medical School.

The title of the paper, which is published in the Proceedings of the National Academy of Sciences, is “Energetic costs and evolutionary implications of human brain development.” Authors include Kuzawa and Leonard as well as Harry T. Chugani, Lawrence I. Grossman, Leonard Lipovich, Otto Muzik, Patrick R. Hof, Derek E. Wildman, Chet C. Sherwood and Nicholas Lange.

The study was funded by the U.S. National Science Foundation’s Biological Anthropology Program.

– See more at: http://www.northwestern.edu/newscenter/stories/2014/08/a-long-childhood-feeds-the-hungry-human-brain.html#sthash.8fxf018q.dpuf

 

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When Furniture Can Tip

furnitureFurniture that can tip is an accident waiting to happen. It a potential source of serious injury for a young child.

In a recent press release, Dr. Alex Rosenau, president of the American College of Emergency Physicians, spoke to the need to inventory our living space for potential sources of tipping and falling objects. He said, “Every parent or guardian of a young child should look around their homes and imagine what could tip over, fall off walls, and injure a child.  Imagining it is better than it becoming a reality.”

The nation’s emergency physicians handle tragic situations too often, but few things are more upsetting than the sudden death of a child killed by a piece of a furniture, appliance or a television falling on them.

About 43,000 people annually were treated in emergency departments between 2009 and 2011 as a result of objects tipping over (such as televisions, dressers, file cabinets, large appliances,) according to the Consumer Product Safety Commission.  Sixty-percent of those emergency visits were from children. In that time span 294 children died–ranging from one-month to 8-years-old.

How to Prevent  Furniture Injuries in Your Home:

  • Properly secure all furniture (especially with shelves, drawers and doors) to walls and remove furniture that is top-heavy and cannot be secured.  Check with home improvement stores or child retail stores and ask experts what they recommend.
  • Secure all computer monitors.
  • Keep television and computer equipment low to the ground.
  • Do not place any objects on top of a television.
  • Place heavy and often-used items low to the ground.
  • Secure or remove artwork that could potentially fall and injure a child, like a sculpture or large painting.
  • Secure appliances such as refrigerators, ovens and microwaves, from tipping over.
  • If you have a mounted television, make sure it’s in a place that’s out or reach for a young child.
  • Put up safety gates to keep young children from rooms that have may have greater risks.

“Telling a child not to touch or climb on something is not enough, said Dr. Rosenau.  “You must take the first steps to prevent tragedy from happening in your home – by childproofing each room they are in.”

SOURCE American College of Emergency Physicians (ACEP)

ACEP is the national medical specialty society representing emergency medicine. ACEP is committed to advancing emergency care through continuing education, research and public education. Headquartered in Dallas, Texas, ACEP has 53 chapters representing each state, as well as Puerto Rico and the District of Columbia. A Government Services Chapter represents emergency physicians employed by military branches and other government agencies.

 

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Who is Drinking all the Diet Beverages?

dietGiven all the concerns about drinking sugary beverages, let’s take a look at who is consuming diet drinks across the U. S.

The following information, posted by the Centers for Disease Control , comes from the National Health and Nutrition Examination Survey, 2009-2010 describes the consumption of diet beverages among the U.S. population during 2009-2010 by sex, age, race and ethnicity, and income, and details trends in diet drink consumption from 1999-2000 through 2009-2010.

About 20% of the U.S. population aged 2 years and over consumed diet drinks on a given day during 2009-2010. The percentage consuming diet drinks was similar for females and males at all ages except among adolescents aged 12-19. The percentage consuming diet drinks increased with age for both males and females. On a given day, about 3% consumed some but no more than 8 fluid ounces (fl oz) of diet drinks, and 11% consumed 16 fluid ounces or more.

Although 15.3% of non-Hispanic white children and adolescents consumed diet drinks, only 6.8% of non-Hispanic black and 7.5% of Hispanic children and adolescents consumed any diet drink on a given day during 2009-2010. Similarly, 27.9% of non-Hispanic white adults consumed any diet drink on a given day compared with 10.1% of non-Hispanic black and 14.1% of Hispanic adults.

The percentage of higher-income persons who consumed diet drinks on a given day was greater than that of lower-income persons. A total of 18.3% of children and adolescents living in households with income at or above 350% of the poverty line consumed diet drinks, compared with 11.5% of those living between 130% and 350% of the poverty line, and 8.0% of those living below 130% of the poverty line. A similar pattern was observed for adults: Although 32.6% of adults living at or above 350% of the poverty line consumed diet drinks, only 20.1% of those living between 130% and 350% of the poverty line, and 12.2% of those living below 130% of the poverty line, consumed diet drinks.

Summary:

Overall, the percentage consuming diet drinks was higher among females compared with males. Diet drink consumption differed by age, race and ethnicity, and income. For example, the percentage of non-Hispanic white children and adults who consumed diet drinks was higher than those for non-Hispanic black and Hispanic children and adults, and the percentage of higher-income persons who consumed diet drinks was higher than that for lower-income persons.

The percentage of females and males who consumed diet drinks increased between 1999 and 2010 and was mirrored by a decrease in consumption of added sugar calories in regular soda over a similar time period. These results suggest that sugar drinks may have been replaced with diet drinks during that time.

Although substituting sugar drinks with diet drinks may promote weight loss in the short term it is unclear if long-term consumption leads to weight loss, weight maintenance, or even weight gain.

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Free Play and Life Skills Development

playA growing number of psychologists believe that changes in the way children play and what they play at and with has also changed kids’ cognitive and emotional development.

As it turns out, time spent in make-believe play, in free play, which allows a child use his or her imagination rather than engaging in structured play activities helps children develop a critical cognitive skill called executive function. Executive function has a number of elements, but a critical element is the ability to self-regulate. Kids with have good self-regulation are able to control their emotions and behavior, resist impulses, and exert self-control and self discipline.

A study done a few years ago replicated a study of self-regulation first done in the late 1940s, in which psychological researchers asked kids ages 3, 5 and 7 to do a number of exercises. One of those exercises included standing perfectly still without moving. The 3-year-olds couldn’t stand still at all, the 5-year-olds could do it for about three minutes, and the 7-year-olds could stand pretty much as long as the researchers asked. In 2001, researchers repeated this experiment. But, psychologist Elena Bodrova at Mid-Continent Research for Education and Learning says, the results were very different.

“Today’s 5-year-olds were acting at the level of 3-year-olds 60 years ago, and today’s 7-year-olds were barely approaching the level of a 5-year-old 60 years ago,” Bodrova explains. “So the results were very sad.”

Poor executive function is associated with high dropout rates, drug use and crime. In fact, good executive function is a better predictor of success in school than a child’s IQ. Children who are able to manage their feelings and pay attention are better able to learn. As executive function researcher Laura Berk explains, “Self-regulation predicts effective development in virtually every domain.”

According to Berk, one reason make-believe play is such a powerful tool for building self-discipline is because during make-believe, children engage in what’s called private speech: They talk to themselves about what they are going to do and how they are going to do it.

“In fact, if we compare preschoolers’ activities and the amount of private speech that occurs across them, we find that this self-regulating language is highest during make-believe play,” Berk says. “And this type of self-regulating language has been shown in many studies to be predictive of executive functions.

Unfortunately, the more structured the play, the more children’s private speech declines. Essentially, because children’s play is so focused on lessons and leagues, and because kids’ toys increasingly inhibit imaginative play, kids aren’t getting a chance to practice policing themselves. When they have that opportunity, says Berk, the results are clear: Self-regulation improves.”

According to Yale psychological researcher Dorothy Singer, teachers and school administrators just don’t see the value and benefits of imaginative play and such play is in decline.

“Because of the testing, and the emphasis now that you have to really pass these tests, teachers are starting earlier and earlier to drill the kids in their basic fundamentals, play is viewed as unnecessary, a waste of time,” Singer says. “I have so many articles that have documented the shortening of free play for children, where the teachers in these schools are using the time for cognitive skills.”

As on psychologist summed it up, “With an ever growing focus on giving children every advantage our culture has unwittingly compromised one of the activities that helped children most.”

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Pets Can Get Sick From Being Fed Raw Foods

The FDA warns about feeding our pets raw foods. In a recent article, this is what they had to say about what can occur when we do.

raw

Raw pet food consists primarily of meat, bones, and organs that haven’t been cooked, and therefore are more likely than cooked food to contain organisms that can make your dog or cat sick, says William J. Burkholder, DVM, PhD, Veterinary Medical Officer in the Food and Drug Administration’s (FDA’s) Division of Animal Feeds. Moreover, raw food can make you sick as well if you don’t handle it properly. FDA does not believe feeding raw pet foods to animals is consistent with the goal of protecting the public from significant health risks.

The agency therefore recommends cooking of raw meat and poultry to kill harmful bacteria like Salmonella and Listeria monocytogenes before you give the food to your pets. And as always, when working with food, you should follow FDA’s instructions on how to handle it safely.

Salmonella bacteria are commonly found in such foods as raw or undercooked meat, poultry, eggs and egg products. Salmonella can also contaminate raw or unpasteurized milk and other dairy products, as well as raw fruits and vegetables.

Burkholder says people who choose a raw diet for their pets often point out that feral dogs and cats catch prey and eat it raw. “That’s true,” he adds, “but we don’t know how many of these animals get sick or die as a result of doing that. Since sick feral animals are rarely taken to a veterinarian when they’re ill, there’s no way to collect that information.”

Symptoms of salmonellosis in animals include:

  • Vomiting
  • Diarrhea (which may be bloody)
  • Fever
  • Loss of appetite
  • Decreased activity level

Listeria bacteria are commonly found in uncooked meats, vegetables and unpasteurized milk and soft cheeses. Unlike most bacteria, Listeria like cold temperatures and can grow and spread in the refrigerator. So if you refrigerate Listeria-contaminated food, the germs not only multiply at the cool temperature, they could contaminate your refrigerator and spread to other foods there, increasing the likelihood that you and your family members would be exposed to Listeria and get sick.

Symptoms of listeriosis in animals include:

  • Nausea
  • Diarrhea
  • Fever
  • Neurological disease can happen in a small percentage of situations

Consumers also run the risk of getting sick if they handle contaminated pet foods and accidentally transfer the bacteria to their mouths.

“If you’re going to handle raw foods, you need to pay particular attention to good hygienic practices,” Burkholder says. “Wash your hands and anything else that comes into contact with the product with hot, soapy water for at least 20 seconds.” Feeding raw food to a pet also increases the risk of contaminating food contact surfaces and other places.

“Even if the dog or cat doesn’t get sick, they can become carriers of Salmonella and transfer the bacteria to their surroundings, and then people can get the disease from contact with the infected environment,” Burkholder says.

Once Salmonella gets established in the pet’s gastrointestinal tract, the animal can shed the bacteria when it has a bowel movement, and the contamination will continue to spread.

Salmonella infection (salmonellosis) symptoms in humans include:

  • Fever
  • Nausea
  • Vomiting
  • Diarrhea (which may be bloody)
  • Stomach pain
  • More rarely: entry of Salmonella into bloodstream from intestines, followed by spread to joints, arteries, heart, soft tissues, and other areas of body

Symptoms associated with salmonellosis most often begin 12 hours to 3 days after ingestion of the bacteria and can last 4 to 7 days without treatment. All consumers are at risk for contracting salmonellosis from contaminated foods, but pregnant women, children under five, the elderly and those with weak immune systems are at risk of developing severe symptoms.

Compared to salmonellosis and other foodborne illnesses, infection with Listeria monocytogenes (listeriosis) is rare, but has serious and potentially fatal risks.

Listeria can infect multiple locations in the body:

  • The brain
  • Membranes surrounding the brain and spinal cord
  • Gastrointestinal tract
  • Bloodstream

Symptoms associated with listeriosis begin 11 to 70 days after coming in contact with the bacteria, with a mean (or average) of 31 days, and they can last up to a few weeks. Listeriosis occurs almost exclusively in pregnant women and their fetuses, newborns, the elderly and those with weak immune systems. Listeriosis can cause life-threatening infection in a fetus and newborns, as well as in persons with weakened immune systems, although the infection can often be treated with antibiotics.

“Feeding raw foods to pets increases the risk that both the pet and the people around the pet will encounter bacteria that cause foodborne illness, particularly if the products are not carefully handled and fed,” Burkholder says. “This is certainly one factor that should be considered when selecting diets for your pet.”

This article appears on FDA’s Consumer Updates page, which features the latest on all FDA-regulated products.

June 30, 2014

 

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